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N-Carbethoxy-4-piperidone

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  • N-Carbethoxy-4-piperidone
  • N-Carbethoxy-4-piperidone

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N-Carbethoxy-4-piperidone

English Name ： N-Carbethoxy-4-piperidone
English Synonyms ：Ethyl 4-oxopiperidine-1-carboxylate; 1-Ethoxycarbonyl-4-piperidone; 4-Oxo-1-piperidinecarboxylic acid ethyl ester; [15 additional aliases condensed]
CAS Number ：29976-53-2
EINECS Number ：249-984-5
Molecular Formula ：C₈H₁₃NO₃
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Product Description

English NameN-Carbethoxy-4-piperidone
English SynonymsEthyl 4-oxopiperidine-1-carboxylate; 1-Ethoxycarbonyl-4-piperidone; 4-Oxo-1-piperidinecarboxylic acid ethyl ester; [15 additional aliases condensed]
CAS Number29976-53-2
EINECS Number249-984-5
Molecular FormulaC₈H₁₃NO₃
Molecular Weight171.1937 g/mol
InChIInChI=1S/C₈H₁₃NO₃/c1-2-12-8(11)9-5-3-7(10)4-6-9/h2-6H₂,1H₃
Molecular Structure

N-乙氧羰基-4-哌啶酮

Density1.155 g/cm³ (Lit. value: 1.135 g/mL at 25°C)
Boiling Point273.4°C at 760 mmHg (Lit. value: 95-98°C at 1 mmHg)
Flash Point87.8°C (Lit. value: 190°F/87.8°C)
Water SolubilitySlightly soluble
Vapor Pressure0.00574 mmHg (5.74×10⁻³ mmHg) at 25°C
Physicochemical Properties• Appearance: Pale yellow liquid
• Refractive Index: 1.475 (n20D)
• Stability: Stable under normal conditions
• Storage: Keep away from ignition sources, sealed container, cool/dry/ventilated area
ApplicationsKey intermediate for Loratadine (antihistamine drug)
Hazard Symbol


Xn: Harmful

Risk PhrasesR22: Harmful if swallowed
R36/38: Irritating to eyes and skin
Safety PhrasesS26: In case of contact with eyes, rinse immediately
S37/39: Wear suitable gloves and eye/face protection
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